AustralieFrV1, Main, Exploration, bibRecord, 005411

Diagnosis of Lung Cancer in Small Biopsies and Cytology

Identifieur interne : 005411 ( Main/Exploration ); précédent : 005410; suivant : 005412

Diagnosis of Lung Cancer in Small Biopsies and Cytology

Auteurs : William D. Travis ; Elisabeth Brambilla ; Masayuki Noguchi ; Andrew G. Nicholson ; Kim Geisinger ; Yasushi Yatabe ; Yuichi Ishikawa ; Ignacio Wistuba ; Douglas B. Flieder ; Wilbur Franklin ; Adi Gazdar ; Philip S. Hasleton ; Douglas W. Henderson ; Keith M. Kerr ; Iver Petersen ; Victor Roggli ; Erik Thunnissen ; Ming Tsao

Source :

Archives of pathology & laboratory medicine [ 0003-9985 ] ; 2012.

RBID : PMC:4509741

Abstract

The new International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society lung adenocarcinoma classification provides, for the first time, standardized terminology for lung cancer diagnosis in small biopsies and cytology; this was not primarily addressed by previous World Health Organization classifications. Until recently there have been no therapeutic implications to further classification of NSCLC, so little attention has been given to the distinction of adenocarcinoma and squamous cell carcinoma in small tissue samples. This situation has changed dramatically in recent years with the discovery of several therapeutic options that are available only to patients with adenocarcinoma or NSCLC, not otherwise specified, rather than squamous cell carcinoma. This includes recommendation for use of special stains as an aid to diagnosis, particularly in the setting of poorly differentiated tumors that do not show clear differentiation by routine light microscopy. A limited diagnostic workup is recommended to preserve as much tissue for molecular testing as possible. Most tumors can be classified using a single adenocarcinoma marker (eg, thyroid transcription factor 1 or mucin) and a single squamous marker (eg, p40 or p63). Carcinomas lacking clear differentiation by morphology and special stains are classified as NSCLC, not otherwise specified. Not otherwise specified carcinomas that stain with adenocarcinoma markers are classified as NSCLC, favor adenocarcinoma, and tumors that stain only with squamous markers are classified as NSCLC, favor squamous cell carcinoma. The need for every institution to develop a multidisciplinary tissue management strategy to obtain these small specimens and process them, not only for diagnosis but also for molecular testing and evaluation of markers of resistance to therapy, is emphasized.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509741

DOI: 10.5858/arpa.2012-0263-RA
PubMed: 22970842
PubMed Central: 4509741

Affiliations:

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Diagnosis of Lung Cancer in Small Biopsies and Cytology</title>
<author><name sortKey="Travis, William D" sort="Travis, William D" uniqKey="Travis W" first="William D." last="Travis">William D. Travis</name>
</author>
<author><name sortKey="Brambilla, Elisabeth" sort="Brambilla, Elisabeth" uniqKey="Brambilla E" first="Elisabeth" last="Brambilla">Elisabeth Brambilla</name>
</author>
<author><name sortKey="Noguchi, Masayuki" sort="Noguchi, Masayuki" uniqKey="Noguchi M" first="Masayuki" last="Noguchi">Masayuki Noguchi</name>
</author>
<author><name sortKey="Nicholson, Andrew G" sort="Nicholson, Andrew G" uniqKey="Nicholson A" first="Andrew G." last="Nicholson">Andrew G. Nicholson</name>
</author>
<author><name sortKey="Geisinger, Kim" sort="Geisinger, Kim" uniqKey="Geisinger K" first="Kim" last="Geisinger">Kim Geisinger</name>
</author>
<author><name sortKey="Yatabe, Yasushi" sort="Yatabe, Yasushi" uniqKey="Yatabe Y" first="Yasushi" last="Yatabe">Yasushi Yatabe</name>
</author>
<author><name sortKey="Ishikawa, Yuichi" sort="Ishikawa, Yuichi" uniqKey="Ishikawa Y" first="Yuichi" last="Ishikawa">Yuichi Ishikawa</name>
</author>
<author><name sortKey="Wistuba, Ignacio" sort="Wistuba, Ignacio" uniqKey="Wistuba I" first="Ignacio" last="Wistuba">Ignacio Wistuba</name>
</author>
<author><name sortKey="Flieder, Douglas B" sort="Flieder, Douglas B" uniqKey="Flieder D" first="Douglas B." last="Flieder">Douglas B. Flieder</name>
</author>
<author><name sortKey="Franklin, Wilbur" sort="Franklin, Wilbur" uniqKey="Franklin W" first="Wilbur" last="Franklin">Wilbur Franklin</name>
</author>
<author><name sortKey="Gazdar, Adi" sort="Gazdar, Adi" uniqKey="Gazdar A" first="Adi" last="Gazdar">Adi Gazdar</name>
</author>
<author><name sortKey="Hasleton, Philip S" sort="Hasleton, Philip S" uniqKey="Hasleton P" first="Philip S." last="Hasleton">Philip S. Hasleton</name>
</author>
<author><name sortKey="Henderson, Douglas W" sort="Henderson, Douglas W" uniqKey="Henderson D" first="Douglas W." last="Henderson">Douglas W. Henderson</name>
</author>
<author><name sortKey="Kerr, Keith M" sort="Kerr, Keith M" uniqKey="Kerr K" first="Keith M." last="Kerr">Keith M. Kerr</name>
</author>
<author><name sortKey="Petersen, Iver" sort="Petersen, Iver" uniqKey="Petersen I" first="Iver" last="Petersen">Iver Petersen</name>
</author>
<author><name sortKey="Roggli, Victor" sort="Roggli, Victor" uniqKey="Roggli V" first="Victor" last="Roggli">Victor Roggli</name>
</author>
<author><name sortKey="Thunnissen, Erik" sort="Thunnissen, Erik" uniqKey="Thunnissen E" first="Erik" last="Thunnissen">Erik Thunnissen</name>
</author>
<author><name sortKey="Tsao, Ming" sort="Tsao, Ming" uniqKey="Tsao M" first="Ming" last="Tsao">Ming Tsao</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">22970842</idno>
<idno type="pmc">4509741</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509741</idno>
<idno type="RBID">PMC:4509741</idno>
<idno type="doi">10.5858/arpa.2012-0263-RA</idno>
<date when="2012">2012</date>
<idno type="wicri:Area/Pmc/Corpus">001F61</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001F61</idno>
<idno type="wicri:Area/Pmc/Curation">001E15</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001E15</idno>
<idno type="wicri:Area/Pmc/Checkpoint">001F82</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001F82</idno>
<idno type="wicri:Area/Ncbi/Merge">000F71</idno>
<idno type="wicri:Area/Ncbi/Curation">000F71</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000F71</idno>
<idno type="wicri:doubleKey">0003-9985:2012:Travis W:diagnosis:of:lung</idno>
<idno type="wicri:Area/Main/Merge">005659</idno>
<idno type="wicri:Area/Main/Curation">005411</idno>
<idno type="wicri:Area/Main/Exploration">005411</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Diagnosis of Lung Cancer in Small Biopsies and Cytology</title>
<author><name sortKey="Travis, William D" sort="Travis, William D" uniqKey="Travis W" first="William D." last="Travis">William D. Travis</name>
</author>
<author><name sortKey="Brambilla, Elisabeth" sort="Brambilla, Elisabeth" uniqKey="Brambilla E" first="Elisabeth" last="Brambilla">Elisabeth Brambilla</name>
</author>
<author><name sortKey="Noguchi, Masayuki" sort="Noguchi, Masayuki" uniqKey="Noguchi M" first="Masayuki" last="Noguchi">Masayuki Noguchi</name>
</author>
<author><name sortKey="Nicholson, Andrew G" sort="Nicholson, Andrew G" uniqKey="Nicholson A" first="Andrew G." last="Nicholson">Andrew G. Nicholson</name>
</author>
<author><name sortKey="Geisinger, Kim" sort="Geisinger, Kim" uniqKey="Geisinger K" first="Kim" last="Geisinger">Kim Geisinger</name>
</author>
<author><name sortKey="Yatabe, Yasushi" sort="Yatabe, Yasushi" uniqKey="Yatabe Y" first="Yasushi" last="Yatabe">Yasushi Yatabe</name>
</author>
<author><name sortKey="Ishikawa, Yuichi" sort="Ishikawa, Yuichi" uniqKey="Ishikawa Y" first="Yuichi" last="Ishikawa">Yuichi Ishikawa</name>
</author>
<author><name sortKey="Wistuba, Ignacio" sort="Wistuba, Ignacio" uniqKey="Wistuba I" first="Ignacio" last="Wistuba">Ignacio Wistuba</name>
</author>
<author><name sortKey="Flieder, Douglas B" sort="Flieder, Douglas B" uniqKey="Flieder D" first="Douglas B." last="Flieder">Douglas B. Flieder</name>
</author>
<author><name sortKey="Franklin, Wilbur" sort="Franklin, Wilbur" uniqKey="Franklin W" first="Wilbur" last="Franklin">Wilbur Franklin</name>
</author>
<author><name sortKey="Gazdar, Adi" sort="Gazdar, Adi" uniqKey="Gazdar A" first="Adi" last="Gazdar">Adi Gazdar</name>
</author>
<author><name sortKey="Hasleton, Philip S" sort="Hasleton, Philip S" uniqKey="Hasleton P" first="Philip S." last="Hasleton">Philip S. Hasleton</name>
</author>
<author><name sortKey="Henderson, Douglas W" sort="Henderson, Douglas W" uniqKey="Henderson D" first="Douglas W." last="Henderson">Douglas W. Henderson</name>
</author>
<author><name sortKey="Kerr, Keith M" sort="Kerr, Keith M" uniqKey="Kerr K" first="Keith M." last="Kerr">Keith M. Kerr</name>
</author>
<author><name sortKey="Petersen, Iver" sort="Petersen, Iver" uniqKey="Petersen I" first="Iver" last="Petersen">Iver Petersen</name>
</author>
<author><name sortKey="Roggli, Victor" sort="Roggli, Victor" uniqKey="Roggli V" first="Victor" last="Roggli">Victor Roggli</name>
</author>
<author><name sortKey="Thunnissen, Erik" sort="Thunnissen, Erik" uniqKey="Thunnissen E" first="Erik" last="Thunnissen">Erik Thunnissen</name>
</author>
<author><name sortKey="Tsao, Ming" sort="Tsao, Ming" uniqKey="Tsao M" first="Ming" last="Tsao">Ming Tsao</name>
</author>
</analytic>
<series><title level="j">Archives of pathology & laboratory medicine</title>
<idno type="ISSN">0003-9985</idno>
<idno type="eISSN">1543-2165</idno>
<imprint><date when="2012">2012</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p id="P1">The new International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society lung adenocarcinoma classification provides, for the first time, standardized terminology for lung cancer diagnosis in small biopsies and cytology; this was not primarily addressed by previous World Health Organization classifications. Until recently there have been no therapeutic implications to further classification of NSCLC, so little attention has been given to the distinction of adenocarcinoma and squamous cell carcinoma in small tissue samples. This situation has changed dramatically in recent years with the discovery of several therapeutic options that are available only to patients with adenocarcinoma or NSCLC, not otherwise specified, rather than squamous cell carcinoma. This includes recommendation for use of special stains as an aid to diagnosis, particularly in the setting of poorly differentiated tumors that do not show clear differentiation by routine light microscopy. A limited diagnostic workup is recommended to preserve as much tissue for molecular testing as possible. Most tumors can be classified using a single adenocarcinoma marker (eg, thyroid transcription factor 1 or mucin) and a single squamous marker (eg, p40 or p63). Carcinomas lacking clear differentiation by morphology and special stains are classified as NSCLC, not otherwise specified. Not otherwise specified carcinomas that stain with adenocarcinoma markers are classified as NSCLC, favor adenocarcinoma, and tumors that stain only with squamous markers are classified as NSCLC, favor squamous cell carcinoma. The need for every institution to develop a multidisciplinary tissue management strategy to obtain these small specimens and process them, not only for diagnosis but also for molecular testing and evaluation of markers of resistance to therapy, is emphasized.</p>
</div>
</front>
</TEI>
<affiliations><list></list>
<tree><noCountry><name sortKey="Brambilla, Elisabeth" sort="Brambilla, Elisabeth" uniqKey="Brambilla E" first="Elisabeth" last="Brambilla">Elisabeth Brambilla</name>
<name sortKey="Flieder, Douglas B" sort="Flieder, Douglas B" uniqKey="Flieder D" first="Douglas B." last="Flieder">Douglas B. Flieder</name>
<name sortKey="Franklin, Wilbur" sort="Franklin, Wilbur" uniqKey="Franklin W" first="Wilbur" last="Franklin">Wilbur Franklin</name>
<name sortKey="Gazdar, Adi" sort="Gazdar, Adi" uniqKey="Gazdar A" first="Adi" last="Gazdar">Adi Gazdar</name>
<name sortKey="Geisinger, Kim" sort="Geisinger, Kim" uniqKey="Geisinger K" first="Kim" last="Geisinger">Kim Geisinger</name>
<name sortKey="Hasleton, Philip S" sort="Hasleton, Philip S" uniqKey="Hasleton P" first="Philip S." last="Hasleton">Philip S. Hasleton</name>
<name sortKey="Henderson, Douglas W" sort="Henderson, Douglas W" uniqKey="Henderson D" first="Douglas W." last="Henderson">Douglas W. Henderson</name>
<name sortKey="Ishikawa, Yuichi" sort="Ishikawa, Yuichi" uniqKey="Ishikawa Y" first="Yuichi" last="Ishikawa">Yuichi Ishikawa</name>
<name sortKey="Kerr, Keith M" sort="Kerr, Keith M" uniqKey="Kerr K" first="Keith M." last="Kerr">Keith M. Kerr</name>
<name sortKey="Nicholson, Andrew G" sort="Nicholson, Andrew G" uniqKey="Nicholson A" first="Andrew G." last="Nicholson">Andrew G. Nicholson</name>
<name sortKey="Noguchi, Masayuki" sort="Noguchi, Masayuki" uniqKey="Noguchi M" first="Masayuki" last="Noguchi">Masayuki Noguchi</name>
<name sortKey="Petersen, Iver" sort="Petersen, Iver" uniqKey="Petersen I" first="Iver" last="Petersen">Iver Petersen</name>
<name sortKey="Roggli, Victor" sort="Roggli, Victor" uniqKey="Roggli V" first="Victor" last="Roggli">Victor Roggli</name>
<name sortKey="Thunnissen, Erik" sort="Thunnissen, Erik" uniqKey="Thunnissen E" first="Erik" last="Thunnissen">Erik Thunnissen</name>
<name sortKey="Travis, William D" sort="Travis, William D" uniqKey="Travis W" first="William D." last="Travis">William D. Travis</name>
<name sortKey="Tsao, Ming" sort="Tsao, Ming" uniqKey="Tsao M" first="Ming" last="Tsao">Ming Tsao</name>
<name sortKey="Wistuba, Ignacio" sort="Wistuba, Ignacio" uniqKey="Wistuba I" first="Ignacio" last="Wistuba">Ignacio Wistuba</name>
<name sortKey="Yatabe, Yasushi" sort="Yatabe, Yasushi" uniqKey="Yatabe Y" first="Yasushi" last="Yatabe">Yasushi Yatabe</name>
</noCountry>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 005411 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 005411 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Asie
   |area=    AustralieFrV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     PMC:4509741
   |texte=   Diagnosis of Lung Cancer in Small Biopsies and Cytology
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:22970842" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a AustralieFrV1

This area was generated with Dilib version V0.6.33.
Data generation: Tue Dec 5 10:43:12 2017. Site generation: Tue Mar 5 14:07:20 2024

Serveur d'exploration sur les relations entre la France et l'Australie

Diagnosis of Lung Cancer in Small Biopsies and Cytology

Diagnosis of Lung Cancer in Small Biopsies and Cytology

Source :

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur les relations entre la France et l'Australie
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.